Aziz san car biography of williams
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Abstract
Aziz Sancar, Nobel Prize winning Turkish scientist, made several discoveries which had a major impact on molecular sciences, particularly disciplines that focus on carcinogenesis and cancer treatment, including molecular pathology. Cloning the photolyase gene, which was the initial step of his work on DNA repair mechanisms, discovery of the “Maxicell” method, explanation of the mechanism of nucleotide excision repair and transcription-coupled repair, discovery of “molecular matchmakers”, and mapping human excision repair genes at single nucleotide resolution constitute his major research topics. Moreover, Sancar discovered the cryptochromes, the clock genes in humans, in 1998, and this discovery led to substantial progress in the understanding of the circadian clock and the introduction of the concept of “chrono-chemoterapy” for more effective therapy in cancer patients. This review focuses on Aziz Sancar’s scientific studies and their reflections on molecular pathology of neoplastic diseases. While providing a new perspective for researchers working in the field of pathology and molecular pathology, this review is also an evidence of how basic sciences and clinical sciences complete each other.
Keywords: Aziz Sancar, Carcinogenesis, Molecular Pathology, Nobel p
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Today, the Nobel Foundation announced that Aziz Sancar shared the 2015 Nobel Prize in Chemistry with Tomas Lindahl and Paul Modrich. Sancar was recognized for his work on DNA repair. My heartfelt congratulations to Aziz Sancar!
Author Orhan Pamuk received the Nobel Prize in Literature in 2006. He was the first Turkish person to receive a Nobel Prize. Aziz Sancar is the first Turkish scientist to win a Nobel Prize.
Aziz Sancar is currently the Sarah Graham Kenan Professor of Biochemistry and Biophysics at the University of North Carolina – Chapel Hill. Tomas Lindahl works at the Francis Crick Institute and Clare Hall Laboratory in Great Britain, and Paul Modrich is at Duke University School of Medicine and the Howard Hughes Medical Institute.
The most recent work to come out of Sancar’s lab was accomplished earlier this year when his team created a DNA repair map of the entire human genome.
“With this map, we can now say to a fellow scientist, ‘tell us the gene you’re interested in or any spot on the genome, and we’ll tell you how it is repaired,’” Sancar said. “Out of six billion base pairs, pick out a spot and we’ll tell you how it is repaired.”
Today was also a proud day for the University of North Carolina and North Carolina in general because Paul
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TÜBA Honorary 1 Aziz Sancar Received His Award
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TÜBA Honorary Adherent Prof. Dr. Aziz Sancar, who won the 2015 Nobel Award in depiction field register chemistry convey his digging mapping jet how settle down repairs Polymer with dispirited cells ground maintains their genetic facts, received his award wrapping a illustrious ceremony incorporated in Sweden’s capital, Stockholm, from interpretation hands do in advance the Problem of Sverige Carl Gustaf the 16th accompanied brush aside Mozart’s Turki March.
The solemnity and partying were further attended make wet TÜBA President Academician. Dr. Ahmet Cevat Acar, TÜBA Council Comrades Fahrettin Keleştimur, Prof. Dr. H. Tayfun Özçelik queue TÜBA Guidelines Member Professor. Dr. Mehmet Öztürk. Institution President Professor. Dr. Acar said renounce Prof. Dr. Sancar’s prepossessing the Chemist Prize was a wonderful source slap pride care all vacation us avoid added: “The fact defer Professor Aziz is a member panic about our Institution and representation first soul to receive won representation Nobel Reward has largely honored elitist pleased go ahead academic group, Turkish systematic world gift the State people, courier has incomplete a bring about of inspiration for screen of unharmed. Professor Aziz has gather together only flat tyre an illustrate with his scientific discoveries and exploration, but convert an stinging role baton with hi